The Molecular Genetics Laboratories at Black Hills State University are equipped for DNA sequencing and genotype analysis. The available equipment includes 5 thermocyclers for PCR, a Fotodyne digital imaging system for visualizing and documenting electrophoretic gels, a Genequant microcell ultraspectrophometer used primarily for quantification of DNA samples, 2 automated genetic analyzers (ABI 310 and ABI 3100), as well as other standard laboratory equipment such as micropipetters, centrifuges etc.

The Molecular Genetics Laboratories are also equipped for genomics research and data collection. The available equipment includes an ABI 7000 Sequence Detection System for real-time PCR and gene expression analysis, a MJ Research Opticon II Real Time PCR System for gene expression analysis, and a GenePix 4200 Array Scanner for microarray analysis.